Allogeneic Venous Grafts of Different Origin Used for Portal Vein Reconstruction After Pancreaticoduodenectomy – Experimental Study

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dc.contributor.authorPálek, Richard
dc.contributor.authorJonášová, Alena
dc.contributor.authorRosendorf, Jáchym
dc.contributor.authorMik, Patrik
dc.contributor.authorBajcurová, Kristýna
dc.contributor.authorHošek, Petr
dc.contributor.authorMoulisová, Vladimíra
dc.contributor.authorEberlová, Lada
dc.contributor.authorHaidingerová, Lenka
dc.contributor.authorBrzoň, Ondřej
dc.contributor.authorBednář, Lukáš
dc.contributor.authorKříž, Tomáš
dc.contributor.authorDolanský, Martin
dc.contributor.authorTřeška, Vladislav
dc.contributor.authorTonar, Zbyněk
dc.contributor.authorVimmr, Jan
dc.contributor.authorLiška, Václav
dc.date.accessioned2020-08-31T10:00:20Z
dc.date.available2020-08-31T10:00:20Z
dc.date.issued2019
dc.description.abstract-translatedBackground: In clinical medicine, little is known about the use of allografts for portal vein (PV) reconstruction after pancreaticoduodenectomy (PD). Portal and caval systems are physiologically different, therefore the properties of allografts from caval and portal systems were studied here in a pig model. Materials and Methods: PD with PV reconstruction with allogeneic venous graft from PV or inferior vena cava (IVC) was performed in 26 pigs. Biochemical analysis and ultrasonography measurements were performed during a 4-week monitoring period. Computer simulations were used to evaluate haemodynamics in reconstructed PV and explanted allografts were histologically examined. Results: The native PV and IVC grafts varied in histological structure but were able to adapt morphologically after transplantation. Computer simulation suggested PV grafts to be more susceptible to thrombosis development. Thrombosis of reconstructed PV occurred in four out of five cases in PV group. Conclusion: This study supports the use of allografts from caval system for PV reconstruction in clinical medicine when needed.en
dc.format18 s.cs
dc.format.mimetypeapplication/pdf
dc.identifier.citationPÁLEK, R., JONÁŠOVÁ, A., ROSENDORF, J., MIK, P., BAJCUROVÁ, K., HOŠEK, P., MOULISOVÁ, V., EBERLOVÁ, L., HAIDINGEROVÁ, L., BRZOŇ, O., BEDNÁŘ, L., KŘÍŽ, T., DOLANSKÝ, M., TŘEŠKA, V., TONAR, Z., VIMMR, J., LIŠKA, V. Allogeneic Venous Grafts of Different Origin Used for Portal Vein Reconstruction After Pancreaticoduodenectomy – Experimental Study. ANTICANCER RESEARCH, 2019, roč. 39, č. 12, s. 6603-6620. ISSN 0250-7005.en
dc.identifier.document-number522725300021
dc.identifier.doi10.21873/anticanres.13876
dc.identifier.issn0250-7005
dc.identifier.obd43927895
dc.identifier.uri2-s2.0-85076264760
dc.identifier.urihttp://hdl.handle.net/11025/39533
dc.language.isoenen
dc.project.IDEF17_048/0007280/Aplikace moderních technologií v medicíně a průmyslucs
dc.publisherInternational Institute of Anticancer Researchen
dc.relation.ispartofseriesAnticancer Researchen
dc.rightsPlný text je přístupný v rámci univerzity přihlášeným uživatelům.cs
dc.rights© International Institute of Anticancer Researchen
dc.rights.accessrestrictedAccessen
dc.subject.translatedpancreaticoduodenectomyen
dc.subject.translatedportal vein reconstructionen
dc.subject.translatedallogeneic graftsen
dc.subject.translatedportal vein haemodynamicsen
dc.subject.translatedcomputer blood flow simulationen
dc.titleAllogeneic Venous Grafts of Different Origin Used for Portal Vein Reconstruction After Pancreaticoduodenectomy – Experimental Studyen
dc.typečlánekcs
dc.typearticleen
dc.type.statusPeer-revieweden
dc.type.versionpublishedVersionen

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